Top 3 Supplements to Take When You're Feeling Sick- Salud Healthcare Las Cruces, NM
- Genevieve Montoya
- Apr 16
- 5 min read
When illness strikes, your body needs extra support to fight off infection, reduce inflammation, and restore energy. In addition to rest, hydration, and healthy food, adding targeted supplements can boost your immune response and help you bounce back faster. Whether you're battling a cold, the flu, or just feeling run down, knowing which nutrients to prioritize can make all the difference.

In this blog, we’re breaking down the top 3 supplements to take when feeling sick—Zinc, Ascorbic Acid (Vitamin C), and B-Complex—plus a bonus nutrient you might not be thinking of: Glutathione.
These powerhouse supplements are backed by science and have been shown to support immune health, reduce the duration of illness, and promote overall recovery.
Why Supplementation Matters When You're Sick
When you're sick, your body’s demand for nutrients skyrockets. Your immune system uses vitamins and minerals to create antibodies, fight off pathogens, and repair damaged tissues. Unfortunately, many people are already deficient in key nutrients before they get sick, which may prolong illness and make symptoms worse.
Here are some quick facts that show the importance of immune-boosting supplements:
1 in 3 Americans is deficient in at least one vitamin or mineral critical to immune function.
Studies show that vitamin C and zinc can reduce the duration of cold symptoms by 20-40%.
Low levels of B vitamins are linked to higher levels of stress and a weakened immune system.
Glutathione, known as the body’s “master antioxidant,” helps regulate oxidative stress and inflammation during illness.
Let’s explore how each of these key supplements can help you recover faster and feel better.
Zinc: The Immune System's Frontline Defender
Zinc is one of the most well-researched minerals for immune health. It plays a critical role in the function of white blood cells, which help your body fight off infections. It also helps maintain the integrity of your skin and mucous membranes—your body’s first line of defense against pathogens.
Why Zinc Matters When You're Sick
Reduces the duration and severity of colds and flu
Supports wound healing and tissue repair
Helps regulate inflammation
Essential for immune cell signaling
How to Take Zinc
Recommended dose: 15–40 mg per day when sick
Best taken with food to avoid nausea
Choose high-absorption forms like zinc picolinate, zinc gluconate, or zinc citrate
Note: Taking too much zinc long-term can cause copper imbalance. Use high-dose zinc only temporarily during illness. Be sure to consult your healthcare provider before starting any supplements.
Ascorbic Acid (Vitamin C): Antioxidant Powerhouse
Ascorbic acid, better known as vitamin C, is a potent antioxidant that supports immune cells, reduces inflammation, and helps regenerate other antioxidants in the body. It also helps produce collagen, which is important for healing tissues and strengthening the skin barrier.
Why Vitamin C Is One of the Best Supplements to Take When Feeling Sick
Enhances the production of white blood cells
Reduces the duration and intensity of respiratory infections
Neutralizes harmful free radicals produced during infection
Supports adrenal function to combat stress-related illness
How to Take Vitamin C
Recommended dose: 500 mg to 2000 mg per day in divided doses
Liposomal vitamin C or ascorbic acid powder can improve absorption
Can be taken with or without food
Pro tip: Taking smaller doses (e.g., 500 mg every few hours) may be more effective than one large dose.
B-Complex Vitamins: Stress and Energy Support During Illness
When you’re sick, your energy levels drop, and your body experiences physical and mental stress. B vitamins—especially B6, B9 (folate), and B12—are essential for energy production, red blood cell formation, and proper immune function.
Why B-Complex Is One of the Top Supplements to Take When Feeling Sick
Supports energy metabolism and reduces fatigue
Helps regulate stress hormones
Boosts the production of immune cells
Aids in detoxification and cellular repair
How to Take B-Complex Vitamins
Choose a balanced B-complex that includes B1, B2, B3, B5, B6, B7 (biotin), B9, and B12
Methylated forms (like methylcobalamin and methylfolate) are better absorbed
Take in the morning with food to support daily energy levels
Bonus: Glutathione – The Master Antioxidant
While not always top of mind, glutathione is one of the most powerful nutrients for managing illness. It helps detoxify the body, regulate immune responses, and protect cells from oxidative damage caused by infections.
Glutathione levels tend to drop significantly during illness, especially if you’re dealing with inflammation or oxidative stress (such as during viral infections or chronic fatigue).
Why Glutathione Should Be on Your Radar
Reduces inflammation and oxidative stress
Supports liver detox pathways
Enhances immune cell function
Aids in recovery from illness and stress
How to Take Glutathione
Liposomal glutathione or acetylated glutathione is best for absorption
Recommended dose: 250–500 mg per day when sick
Can be paired with vitamin C to recycle glutathione levels in the body
When to Start Taking Supplements for Illness
The best time to start these supplements is at the first sign of illness—sore throat, fatigue, body aches, or a runny nose. Early intervention with immune-boosting supplements can help:
Reduce symptom severity
Shorten recovery time
Prevent progression into more serious conditions
Even better, these nutrients are safe to take proactively, especially during cold and flu season, periods of high stress, or after exposure to sick individuals.
Quality Matters: Choose Clean, Bioavailable Supplements
To get the most out of your supplements, look for:
Third-party tested products
Bioavailable forms (e.g., zinc citrate, liposomal vitamin C, methylated B vitamins)
Free from fillers, dyes, and unnecessary additives
At Salud Healthcare, we offer access to a discounted online pharmacy that includes high-quality immune support supplements. Our patients receive personalized recommendations, convenient online ordering, and delivery right to your door.
Consult with a Provider Before Starting a New Supplement Routine
While these supplements are safe for most people, always consult your provider—especially if you’re pregnant, breastfeeding, or taking medications. The right dose, form, and combination can vary depending on your age, weight, health status, and medications.
At Salud Healthcare, our primary care team in Las Cruces can help you create a customized immune support plan that’s both effective and affordable.
When you’re feeling sick, the right supplements can make a world of difference. Zinc, ascorbic acid, B-complex vitamins, and glutathione are among the most effective supplements to take when feeling sick, thanks to their role in supporting immune function, reducing inflammation, and accelerating recovery.
Whether you're facing a seasonal cold, managing chronic fatigue, or looking to prevent illness, these nutrients offer a natural, science-backed boost for your body.
Need guidance on what supplements are right for you?
📍 Visit Salud Healthcare in Las Cruces or📞 Call/Text (575) 218-7742 to schedule a consultation.📦 Ask us about our discounted online pharmacy and supplement delivery options!
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